Conformis Highlights New Clinical Study Findings that Knee Shapes are Highly Individualized and are Not Determined by Identifiers, Including Gender, Body Type, or Ethnicity
The study also found that identifiers, such as gender, body type, and ethnicity do not help surgeons determine which off-the-shelf replacement system or implant size will best fit each individual. This recent clinical study further underscores the value of precisely matching a replacement joint with the specific anatomy of each patient.
The absence of predictable shapes or morphotypes “makes it difficult to further reduce the bone to implant mismatch with off-the-shelf implants,” note the authors. Trying to do so, they say, might require an excessive number of sizes of standardized implants that provides significant logistical challenges for facilities. An alternative, they conclude, is the use of customized implants using “patient-specific implant design.”
“This new research reinforces the importance of precisely matching the implant to the individual patient,” said
The authors used two different methodologies to analyze the knee images in an effort to find “clusters” of knees that could provide a way to standardize knee design based on patients’ gender, body type, ethnicity, or other characteristics like age. As expected, the data did not generate any clusters that could be used as predictors to better fit of off-the-shelf implants to the specific anatomies of patients undergoing total knee arthroplasty (TKA).
The article in The Knee follows a retrospective study published in
That earlier study compared patients who had a fully personalized
The authors of the new study concluded, “The data exhibited no morphotypes. This showed that there are no relevant identifiers, e.g., gender, body type, or ethnicity which influence the shape of the knee joint. Instead, knee shape is determined by the unique characteristics of each individual.”
1 Hohlmann, Benjamin, Asseln, Malte, Xu, Jiacheng, Radermacher, Klaus, Investigation of morphotypes of the knee using cluster analysis, The Knee 35 (2002) 157-163 https://www.thekneejournal.com/action/showPdf?pii=S0968-0160%2822%2900034-5
2 Schroeder, Lennart MD1,a; Dunaway, Andrew DO2; Dunaway, Daniel MD3 A Comparison of Clinical Outcomes and Implant Preference of Patients with Bilateral TKA, JBJS Reviews:
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Source: Conformis, Inc.